Vasopressin, Plasma Synonyms ADH; Antidiuretic Hormone; Arginine Vasopressin

Test Includes Osmolality, ADH measurement

Laboratory Core Laboratory

Referral to Reference Laboratory

Request Form Routine Blood Requisition

Phone (212) 305-8600

Availability Daily, 24 hours

Turnaround Time 8 days

Specimen Blood

Volume 6 mL

Minimum Volume Two 3 mL aliquots frozen EDTA plasma

Container Two lavender top (EDTA) tubes

Collection Draw into chilled tubes and place on ice.

Storage Instructions Transport specimen on ice to the laboratory immediately. Centrifuge at 4°C and separate plasma and freeze immediately.

Patient Preparation NPO after midnight. Patient must avoid having radioisotope scan administered 24 hours prior to venipuncture. Patient should be seated and calm during collection.

Causes for Rejection Recently administered radioisotopes

Reference Range If serum osmolality <285 mOsm/L:

2.2 pg/mL; if serum osmolality >290 mOsm/kg: 2.2-8.5 pg/mL

Use Diagnose urine concentration disorders, especially diabetes insipidus, syndrome of inappropriate ADH (SIADH), psychogenic water intoxication, and syndromes of ectopic ADH production

Methodology ADH by radioimmunoassay (RIA)