Use Evaluate hepatobiliary disease, bone disease associated with increased osteoblastic activity, and possible metastatic disease. Pregnant patients and patients with healing fractures may have elevated values. Paget's disease of bone, ingestion of fatty meals, and patients taking many drugs may cause an increase in levels. Other causes of increased levels are hypervitaminosis D, hyperthyroidism, chronic alcohol ingestion, biliary obstruction, cholecystitis with cholangitis, sclerosing cholangitis, primary or metastatic cancer in the liver or bone, cirrhosis, pancreatitis, viral hepatitis, infiltrative liver diseases (such as sarcoid, TB, abscess), pulmonary infarct, renal infarct, and congestive heart failure with passive congestion of the liver.
